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Cyclin E1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 11554-1-AP-150UL
This item is not returnable.
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Description
Cyclin E is a regulatory subunit of Cdk2 and controls G1 / S transition during the mammalian cell cycle. Multiple isoforms of Cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post transcriptional regulation of Cyclin E. In vitro analyses indicated that these truncated variant isoforms of Cyclin E are able to phosphorylate histone H1. Alterations in Cyclin E protein have been implicated as indicators of worse prognosis in various cancers.Specifications
| Cyclin E1 | |
| Polyclonal | |
| Unconjugated | |
| CCNE1 | |
| CCNE, CCNE1, cyclin E1, G1/S specific cyclin E1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 12447, 898 | |
| -20°C | |
| Liquid |
| Flow Cytometry, Western Blot | |
| 0.31 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| P24864, Q61457 | |
| CCNE1 | |
| Cyclin E1 Fusion Protein Ag2110 | |
| 150 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |