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CPI-455, MedChemExpress

Product Code. 16465747
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Product Code. Quantity unitSize
16465747 5 mg 5mg
16464316 100 mg 100mg
16463008 10 mg 10mg
16459576 50 mg 50mg
16412586 25 mg 25mg
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Product Code. 16465747

Brand: Medchem Express HY100421

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Description

MedChemExpress CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents.

CPI-455 is a specific, pan-KDM5 inhibitor with an IC50 of 10 nM for KDM5A. CPI-455 mediates KDM5 inhibition, elevates global levels of H3K4me3, and decreases the number of drug-tolerant persister cancer cells in multiple cancer cell line models treated with standard chemotherapy or targeted agents.

Specifications

Chemical Name or Material CPI-455
Physical Form Solid
CAS 1628208-23-0
Color White
Quantity 5 mg
Purity Grade Notes Research
Molecular Formula C16H14N4O
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : ≥ 34 mg/mL (122.17 mM)
SMILES N#CC1=C2NC(C3=CC=CC=C3)=C(C(C)C)C(N2N=C1)=O
Molecular Weight (g/mol) 278.31
Formula Weight 278.31
Percent Purity 98.11%
Grade Research
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Research purposes only

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