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Cot inhibitor-1, MedChemExpress

Product Code. p-200099886
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Product Code. Quantity unitSize
16483736 25 mg 25mg
16468028 10 mg 10mg
16460336 2 mg 2mg
16450488 5 mg 5mg
16447806 100 mg 100mg
16413957 50 mg 50mg
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Product Code. 16483736

Brand: Medchem Express HY32015

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Description

MedChemExpress Cot inhibitor-1 (compound 28) is a selective tumor progression loci-2 (Tpl2) kinase inhibitor with an IC50 of 28 nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC50 of 5.7 nM.

Cot inhibitor-1 (compound 28) is a selective tumor progression loci-2 (Tpl2) kinase inhibitor with an IC50 of 28 nM. Cot inhibitor-1 shows an inhibition of TNF-alpha production in human whole blood with an IC50 of 5.7 nM.

Specifications

Chemical Name or Material Cot inhibitor-1
CAS 915365-57-0
Color Yellow
Purity Grade Notes Research
Molecular Formula C27H27Cl2FN8
Quantity 25 mg
Solubility Information DMSO : 25 mg/mL (45.17 mM; Need ultrasonic)
SMILES N#CC1=C(C2=CC(NCC3=CN(CCN4CCCCCC4)N=N3)=CC(Cl)=C2N=C1)NC5=CC=C(F)C(Cl)=C5
Molecular Weight (g/mol) 553.46
Formula Weight 553.46
Percent Purity 95.03%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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