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Compound E, MedChemExpress
Description
Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.
Specifications
Specifications
| Chemical Name or Material | Compound E |
| CAS | 209986-17-4 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C27H24F2N4O3 |
| Quantity | 25 mg |
| Synonym | γ-Secretase-IN-1 |
| Solubility Information | DMSO : 115 mg/mL (234.45 mM; ultrasonic and warming and heat to 60°C) |
| SMILES | FC1=CC(CC(N[C@@H](C)C(N[C@@H]2C(N(C)C(C=CC=C3)=C3C(C4=CC=CC=C4)=N2)=O)=O)=O)=CC(F)=C1 |
| Molecular Weight (g/mol) | 490.5 |
| Show More |
Research purposes only
Product Title
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