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Compound E, MedChemExpress

Product Code. 16473406
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Product Code. Quantity unitSize
16473406 25 mg 25mg
16468597 5 mg 5mg
16465978 10 mg 10mg
16451399 1 mg 1mg
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Product Code. 16473406

Brand: Medchem Express HY14176

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MedChemExpress Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.

Compound E is a γ-secretase inhibitor. Compound E bloks β-amyloid(40), β-amyloid(42), and Notch γ-secretase cleavage with IC50s of 0.24, 0.37, 0.32 nM, respectively.

Specifications

Chemical Name or Material Compound E
CAS 209986-17-4
Color White
Purity Grade Notes Research
Molecular Formula C27H24F2N4O3
Quantity 25 mg
Synonym γ-Secretase-IN-1
Solubility Information DMSO : 115 mg/mL (234.45 mM; ultrasonic and warming and heat to 60°C)
SMILES FC1=CC(CC(N[C@@H](C)C(N[C@@H]2C(N(C)C(C=CC=C3)=C3C(C4=CC=CC=C4)=N2)=O)=O)=O)=CC(F)=C1
Molecular Weight (g/mol) 490.5
Formula Weight 490.5
Percent Purity 98.75%
Grade Research
Physical Form Powder
For Use With (Application) Cancer-programmed cell death
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Research purposes only

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