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Invitrogen™ COMP Polyclonal Antibody
GREENER_CHOICE

Rabbit Polyclonal Antibody

Brand:  Invitrogen™ PA596435

Product Code. 16569271

  • 4155.00 NOK / 100µL

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Description

Description

Immunogen sequence: GQGQSPLGSD LGPQMLRELQ ETNAALQDVR ELLRQQVREI TFLKNTVMEC DACGMQQSVR TGLPSVRPLL HCAPGFCFPG VACIQTESGA RCGPCPAGFT GNGSHCTDVN ECNAHPCFPR VRCINTSPGF RCEACPPGYS G; Positive Samples: SW620, U-251MG, HepG2, MCF7, Mouse skeletal muscle; Cellular Location: extracellular matrix, extracellular space.

COMP is a noncollagenous extracellular matrix protein. It consists of five identical glycoprotein subunits, each with EGF like and calcium binding (thrombospondin like) domains. Oligomerization results from formation of a five stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudochondroplasia (PSACH) and multiple epiphyseal dysplasia (MED).
TRUSTED_SUSTAINABILITY
Specifications

Specifications

COMP
Polyclonal
Unconjugated
COMP
Cartilage oligomeric matrix protein; cartilage oligomeric matrix protein (pseudoachondroplasia, epiphyseal dysplasia 1, multiple); cartilage oligomeric matrix protein(pseudoachondroplasia, epiphyseal dysplasia 1, multiple); Comp; EDM1; EPD1; MED; MGC131819; MGC149768; PSACH; pseudoachondroplasia (epiphyseal dysplasia 1, multiple); putative cartilage oligomeric matrix protein; THBS5; Thrombospondin5; Thrombospondin-5; TSP 5; TSP5
Rabbit
Affinity Chromatography
RUO
12845, 1311, 25304
-20°C, Avoid Freeze/Thaw Cycles
Liquid
ELISA, Immunohistochemistry (Paraffin), Western Blot
2.56 mg/mL
PBS with 50% glycerol and 0.05% ProClin 300; pH 7.3
P35444, P49747, Q9R0G6
COMP
Recombinant protein (or fragment).
100 μL
Primary
Human, Mouse, Rat
Antibody
IgG
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