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Invitrogen™ Collagen II Polyclonal Antibody
Rabbit Polyclonal Antibody
Brand: Invitrogen™ PA595138
This item is not returnable.
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Description
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 μg/mL. Positive Control - WB: COLO320 whole cell, HELA whole cell, MCF-7whole cell, A549 whole cell, JURKAT whole cell. Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month. It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.
COL2A1 is the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia.
Specifications
| Collagen II | |
| Polyclonal | |
| Unconjugated | |
| Col2a1 | |
| alpha 1 type II procollagen; alpha 1 type IIA collagen; alpha 1 type IIA collagen precursor; alpha collagen type II; alpha-1 type II collagen; ANFH; AOM; arthroophthalmopathy, progressive (Stickler syndrome); cartilage collagen; CB11; CG2A1A; CGA; Chondrocalcin; COL11A3; Col2; Col2a; col2a1; Col2a-1; col2a1.L; col2a1a; col2a1-a; col2a1-b; Collagen 2; Collagen alpha-1(II) chain; collagen II, alpha-1 polypeptide; collagen type II (Col2A1) gene, enhancer region; collagen type II alpha 1 chain; collagen type IIA; collagen, type II, alpha 1; collagen, type II, alpha 1 (primary osteoarthritis, spondyloepiphyseal dysplasia, congenital); collagen, type II, alpha 1 L homeolog; COLLII; cyanogen bromide; Del1; disproportionate micromelia; Dmm; Lpk; M100856; MGC131516; pro alpha1 type II collagen; pro-alpha 1(II); pro-alpha-1 type II collagen; procollagen alpha 1(II); Procollagen II alpha 1; procollagen, type II, alpha 1; Rgsc856; SEDC; STL1; type II collagen; type II collagen cyanogen bromide fragment CB10; type II collogen cyanogen bromide fragment CB8; unnamed protein product; X-col II; xcol2a1; XELAEV_18013523mg | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 1280, 12824, 25412 | |
| -20°C | |
| Lyophilized |
| Western Blot | |
| 500 μg/mL | |
| PBS with 5mg BSA and 0.05mg sodium azide, 0.05mg thimerosal | |
| P02458, P05539, P28481 | |
| Col2a1 | |
| A synthetic peptide corresponding to a sequence at the C-terminus of human Collagen II (1222-1241aa AFAGLGPREKGPDPLQYMRA). | |
| 100 μg | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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