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Invitrogen™ Procollagen I N-Peptide Polyclonal Antibody
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Product Code. 15276628
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Quantity:
100 μL
Unit Size:
100µL
Product Code. Quantity unitSize
15276628 100 μL 100µL
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Product Code. 15276628

Brand: Invitrogen™ PA535379

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This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

This antibody is predicted to react with most mammals, birds, amphibians and fish based on 100% sequence homology. This antibody contains enough material to conduct 10 mini-Western blots.

Procollagen type I N-terminal propeptide (P1NP) is a specific marker of bone formation, reflecting the synthesis of type I collagen, which constitutes the major part of the bone matrix. P1NP is derived during the conversion of procollagen to collagen, produced by osteoblasts during bone formation. Its primary clinical application lies in the diagnosis and monitoring of metabolic bone diseases, particularly osteoporosis. In osteoporotic patients, P1NP levels can predict bone mineral density (BMD) responses to treatments like teriparatide and romosozumab. Low serum levels of P1NP are indicative of a high risk of BMD loss, providing a valuable tool for premenopausal women with systemic lupus erythematosus (SLE) and other conditions affecting bone health.
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Specifications

Antigen Procollagen I N-Peptide
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.15 mg/mL
Conjugate Unconjugated
Formulation PBS with no preservative; pH 7.5
Gene COL1A1
Gene Accession No. P02452, P02454, P11087
Gene Alias P1NP; Procollagen I N
Gene Symbols COL1A1
Host Species Rabbit
Immunogen Synthetic peptide corresponding to amino acid residues specific to human collagen 1, alpha 1 propeptide conjugated to KLH.
Purification Method Affinity chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 1277, 12842, 29393
Target Species Human, Mouse, Rat
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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