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TOKU-E™ Co-trimoxazole ReadyMade™ Solution
Description
- CAS Number: 8064-90-2
- Molecular Formula: C14H18N4O3 · 5 C10H11N3O3S
- Molecular Weight: 1556.71 g/mol
- Storage Conditions: -20°C
- Form: Liquid
- Source: Synthetic mixture
- Spectrum: Co-trimoxazole is broad-spectrum, active against Gram-negative bacteria, Gram-positive bacteria, fungi, parasites, and some mycobacteria. Non-susceptible organisms include Mycobacterium tuberculosis, Treponema pallidum, Pseudomonas aeruginosa, and Mycoplasma species
- Mechanism of Action: Co-trimoxazole interferes with bacterial folic acid metabolism by blocking nucleotide biosynthesis. Trimethoprim binds to dihydrofolate reductase (DHFR) which blocks the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF) and gives the compound its antimicrobial effect. Sulfamethoxazole interferes with nucleic acid synthesis by blocking conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid. The net result is to inhibit thymine synthesis which in turn prevents the synthesis of bacterial DNA
Specifications
Specifications
| Chemical Name or Material | Co-Trimoxazole, Cotrimoxazol, Benzenesulfonamide |
| Physical Form | Liquid |
| CAS | 8064-90-2 |
| Source | Synthetic; Mixture |
| Packaging | 2 mL plastic vial |
| Sterile Filtered | Yes, 0.22 μm |
| Sterility | Sterile |
| Color | Colorless |
| Concentration | 100 to 105 mg/mL |
| Quantity | 10 x 1 mL |
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