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TOKU-E™ Co-trimoxazole ReadyMade™ Solution

Product Code. 30044017
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10 x 1 mL
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10mL
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Product Code. 30044017 Supplier TOKU-E™ Supplier No. C28710x1ML

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Co-trimoxazole ReadyMade™ Solution is provided as a sterile-filtered solution of Co-trimoxazole in DMSO.

  • CAS Number: 8064-90-2
  • Molecular Formula: C14H18N4O3 · 5 C10H11N3O3S
  • Molecular Weight: 1556.71 g/mol
  • Storage Conditions: -20°C
  • Form: Liquid
  • Source: Synthetic mixture
  • Spectrum: Co-trimoxazole is broad-spectrum, active against Gram-negative bacteria, Gram-positive bacteria, fungi, parasites, and some mycobacteria. Non-susceptible organisms include Mycobacterium tuberculosis, Treponema pallidum, Pseudomonas aeruginosa, and Mycoplasma species
  • Mechanism of Action: Co-trimoxazole interferes with bacterial folic acid metabolism by blocking nucleotide biosynthesis. Trimethoprim binds to dihydrofolate reductase (DHFR) which blocks the reduction of dihydrofolic acid (DHF) to tetrahydrofolic acid (THF) and gives the compound its antimicrobial effect. Sulfamethoxazole interferes with nucleic acid synthesis by blocking conversion of p-aminobenzoic acid to the coenzyme dihydrofolic acid. The net result is to inhibit thymine synthesis which in turn prevents the synthesis of bacterial DNA

Specifications

Chemical Name or Material Co-Trimoxazole, Cotrimoxazol, Benzenesulfonamide
Physical Form Liquid
CAS 8064-90-2
Source Synthetic; Mixture
Packaging 2 mL plastic vial
Sterile Filtered Yes, 0.22 μm
Sterility Sterile
Color Colorless
Concentration 100 to 105 mg/mL
Quantity 10 x 1 mL
Purity Grade Notes >95% (HPLC)
Molecular Formula C14H18N4O3 · 5 C10H11N3O3S
Product Line ReadyMade™ Solutions
Shipping Condition Ice Pack
Synonym Cotrimoxazol, Benzenesulfonamide
IUPAC Name 4-amino-N-(5-methyl-3-isoxazolyl)-, mixture with 5-[(3,4,5-trimethoxyphenyl)methyl]-2,4-pyrimidinediamine
Molecular Weight (g/mol) 1556.71 g/mol
Formula Weight 1556.71 amu
Percent Purity >95%
Grade Antibiotic
Concentration or Composition (by Analyte or Components) Co-Trimoxazole 10%, DMSO 90%
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