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Invitrogen™ Claudin 1 Monoclonal Antibody (2H10D10)
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Product Code. 10332903
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100 μg
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10332903 100 μg Each
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Product Code. 10332903 Supplier Invitrogen™ Supplier No. 374900

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Description

Mouse Monoclonal Antibody

Reactivity has been confirmed with human Caco-2 and canine MDCK cell lysates, mouse kidney and intestinal lysates, frozen mouse intestine (jejunum) tissue, and rat kidney homogenates. This antibody is specific for the C-terminal region of the claudin-1 protein. On western blots, it identifies the target band at ~22 kDa.

Claudin-1 is a member of the transmembrane protein family claudins located in cell-cell tight junctions and it acts as a co-receptor for HCV entry into hepatic cells. Claudins are abundant in luminal epithelial sheets where they maintain epithelial cell polarity. Claudin-1 is expressed in most tissues such as bladder, fallopian tube, liver, pancreas, prostate, and skin.
TRUSTED_SUSTAINABILITY

Specifications

Antigen Claudin 1
Applications ELISA, Immunohistochemistry (Frozen), Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot, Immunocytochemistry
Classification Monoclonal
Clone 2H10D10
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 0.1% sodium azide; pH 7.4
Gene CLDN1
Gene Accession No. O88551, O95832, P56745
Gene Alias AI596271; claudin 1; claudin-1; CLD1; CLDN1; hypothetical protein; ILVASC; SEMP1; Senescence-associated epithelial membrane protein; senescence-associated epithelial membrane protein 1; tight junction protein; UNQ481/PRO944
Gene Symbols CLDN1
Host Species Mouse
Immunogen Synthetic peptide derived from the C-terminal region of the human and mouse claudin-1 proteins.
Purification Method Protein A
Quantity 100 μg
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12737, 608207, 65129, 9076
Target Species Canine, Human, Mouse, Rat
Content And Storage Maintain refrigerated at 2-8°C for up to 1 month. For long term storage store at -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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