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cis-Aconitic anhydride, 98%

Product Code. 11428616
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5 g
25 g
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25g
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Product Code. 11428616

Brand: Thermo Scientific Alfa Aesar A16006.03

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CAS: 6318-55-4 | C6H4O5 | 156.093 g/mol

cis-Aconitic anhydride is used in the preparation of poly(amino acid)-containing copolymers with gradient pH-sensitive side groups initiated by the amino groups in methoxy poly(ethylene glycol)-block-poly(L-lysine). It is also involved in the preparation of pH-sensitive anti-tumor prodrug nanoparticles by conjugation with D-alfa-tocopheryl polyethylene glycol 1000 succinate (TPGS).

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
cis-Aconitic anhydride is used in the preparation of poly(amino acid)-containing copolymers with gradient pH-sensitive side groups initiated by the amino groups in methoxy poly(ethylene glycol)-block-poly(L-lysine). It is also involved in the preparation of pH-sensitive anti-tumor prodrug nanoparticles by conjugation with D-alfa-tocopheryl polyethylene glycol 1000 succinate (TPGS).

Notes
Moisture sensitive. Incompatible with strong acids, strong oxidizing agents and strong bases. Store in a cool place.
TRUSTED_SUSTAINABILITY

Chemical Identifiers

CAS 6318-55-4
Molecular Formula C6H4O5
Molecular Weight (g/mol) 156.093
MDL Number MFCD00005524
InChI Key GVJRTUUUJYMTNQ-UHFFFAOYSA-N
Synonym cis-aconitic anhydride, aconitic anhydride, cis-aconitic acid anhydride, 3-furanacetic acid, 2,5-dihydro-2,5-dioxo, 2-2,5-dioxo-2,5-dihydrofuran-3-yl acetic acid, 2,5-dioxofuran-3-yl acetic acid, 2-2,5-dioxo-3-furyl acetic acid, 1-propene-1,2,3-tricarboxylic acid, cyclic 1,2-anhydride, 2,5-dioxo-2,5-dihydro-furan-3-yl-acetic acid, z-aconitic anhydride
PubChem CID 65163
IUPAC Name 2-(2,5-dioxofuran-3-yl)acetic acid
SMILES C1=C(C(=O)OC1=O)CC(=O)O

Specifications

Melting Point 74°C to 78°C
Quantity 1 g
UN Number UN3261
Beilstein 127575
Sensitivity Moisture sensitive
Formula Weight 156.1
Percent Purity 98%
Chemical Name or Material cis-Aconitic anhydride
compliance-icons
Product Identifier
  • cis-Aconitic anhydride
Signal Word
  • Danger
Hazard Category
  • Serious eye damage/eye irritation Category 1
  • Skin corrosion/irritation Category 1 B
Hazard Statement
  • H314-Causes severe skin burns and eye damage.
  • H318-Causes serious eye damage.
Precautionary Statement
  • P280-Wear protective gloves/protective clothing/eye protection/face protection.
  • P301+P330+P331-IF SWALLOWED: rinse mouth. Do NOT induce vomiting.
  • P303+P361+P353-IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water/ shower.
  • P305+P351+P338-IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
  • P310-Immediately call a POISON CENTER/doctor/.
Supplemental information
  • MIXTURE LIST-Contains : 2,5-dihydro-2,5-dioxo-3-furanacetic acid

RUO – Research Use Only

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