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Cilofexor, MedChemExpress
Description
Cilofexor (GS-9674) is a potent, selective and orally active nonsteroidal FXR agonist with an EC50 of 43 nM. Cilofexor has anti-inflammatory and antifibrotic effects. Cilofexor has the potential for primary sclerosing cholangitis (PSC) and nonalcoholic steatohepatitis (NASH) research.
Specifications
Specifications
| Chemical Name or Material | Cilofexor |
| CAS | 1418274-28-8 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C28H22Cl3N3O5 |
| Quantity | 25 mg |
| Synonym | GS-9674 |
| Solubility Information | DMSO : 50 mg/mL (85.20 mM; Need ultrasonic) |
| SMILES | ClC1=C(C2(CN(C3=CC(C(O)=O)=CC=N3)C2)O)C=CC(OCC4=C(C5CC5)ON=C4C(C(Cl)=CC=C6)=C6Cl)=C1 |
| Molecular Weight (g/mol) | 586.85 |
| Show More |
Research purposes only
Product Title
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