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CHFR Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
1611.84 NOK - 4593.76 NOK
Specifications
Antigen | CHFR |
---|---|
Concentration | 0.27 mg/mL |
Applications | Immunohistochemistry (Paraffin), Western Blot |
Classification | Polyclonal |
Conjugate | Unconjugated |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16899713
|
Proteintech
12169-1-AP-20UL |
20 μL |
1611.84 NOK
20µL |
Estimated Shipment: 15-05-2024 Log in to see stock. |
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16889713
|
Proteintech
12169-1-AP-150UL |
150 μL |
4593.76 NOK
150µL |
Estimated Shipment: 15-05-2024 Log in to see stock. |
Please sign in to purchase this item. Need a web account? Register with us today! | ||||
Description
E3 ubiquitin-protein ligase that functions in the antephase checkpoint by actively delaying passage into mitosis in response to microtubule poisons. Acts in early prophase before chromosome condensation, when the centrosome move apart from each other along the periphery of the nucleus. Probably involved in signaling the presence of mitotic stress caused by microtubule poisons by mediating the ′Lys-48′-linked ubiquitination of target proteins, leading to their degradation by the proteasome. Promotes the ubiquitination and subsequent degradation of AURKA and PLK1. Probably acts as a tumor suppressor, possibly by mediating the polyubiquitination of HDAC1, leading to its degradation. May also promote the formation of ′Lys-63′-linked polyubiquitin chains and functions with the specific ubiquitin-conjugating UBC13-MMS2 (UBE2N-UBE2V2) heterodimer. Substrates that are polyubiquitinated at ′Lys-63′ are usually not targeted for degradation, but are rather involved in signaling cellular stress.Specifications
CHFR | |
Immunohistochemistry (Paraffin), Western Blot | |
Unconjugated | |
Rabbit | |
Human, Mouse, Rat | |
Q810L3, Q96EP1 | |
231600, 288734, 55743 | |
CHFR Fusion Protein Ag2811 | |
Primary | |
-20°C | |
CHFR |
0.27 mg/mL | |
Polyclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
CHFR, RING finger protein 196, RNF116, RNF196 | |
Chfr | |
IgG | |
Antigen Affinity Chromatography | |
Antibody |