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Chemerin Monoclonal Antibody (E10), Invitrogen™
Mouse Monoclonal Antibody
Brand: Invitrogen MA543889
Additional Details : Weight : 0.01000kg
Description
Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.Specifications
Chemerin | |
Monoclonal | |
1 mg/mL | |
PBS with 50% glycerol and 0.05% ProClin 300 | |
Q99969 | |
Rarres2 | |
Ala33-Lys158 (Accession Q99969), with N-terminal His Tag | |
100 μL | |
Primary | |
Human | |
Antibody | |
IgG2b κ |
Immunohistochemistry (Paraffin), Western Blot | |
E10 | |
Unconjugated | |
Rarres2 | |
0610007L05Rik; AI303516; Chemerin; HP10433; Rarres2; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; retinoic acid receptor responder 2; retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG2; TIG-2; TIG2HP10433 | |
Mouse | |
Protein A/G | |
RUO | |
5919 | |
-20°C | |
Liquid |