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Chemerin Monoclonal Antibody (E10), Invitrogen™

Mouse Monoclonal Antibody

Brand:  Invitrogen MA543889

Additional Details : Weight : 0.01000kg

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Product Code. 17634346

  • 4125.00 NOK / 100µL
Estimated Shipment: 03-06-2024
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Description

Description

Retinoids act through ligand-dependent transcription factors, retinoid X receptor (RXRs) and retinoic acid receptors (RARs). Tazarotene-induced gene (TIG) proteins, also designated retinoic acid receptor responder proteins or RAR-responsive proteins, can be membrane bound or secreted. TIGs act as tumor suppressor genes in human cancers and are highly expressed in skin, hair follicles and endothelial cells as well as in pancreas, spleen and intestine. TIGs are activated by tazarotene and have been implicated as growth regulators that mediate the growth suppressive effects of retinoids. TIG2 is a secreted protein that is mainly expressed in epidermis, hair follicles and endothelial cells. TIG2 is inhibited in psoriatic lesions and is activated by tazarotene in skin rafts and in epidermis of psoriatic lesions.
Specifications

Specifications

Chemerin
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.05% ProClin 300
Q99969
Rarres2
Ala33-Lys158 (Accession Q99969), with N-terminal His Tag
100 μL
Primary
Human
Antibody
IgG2b κ
Immunohistochemistry (Paraffin), Western Blot
E10
Unconjugated
Rarres2
0610007L05Rik; AI303516; Chemerin; HP10433; Rarres2; RAR-responsive protein TIG2; retinoic acid receptor responder (tazarotene induced) 2; retinoic acid receptor responder 2; retinoic acid receptor responder protein 2; Tazarotene-induced gene 2 protein; TIG2; TIG-2; TIG2HP10433
Mouse
Protein A/G
RUO
5919
-20°C
Liquid
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