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CHCHD6 Mouse anti-Human, Clone: 2A11E9, Proteintech
Mouse Monoclonal Antibody
1611.84 NOK - 4593.76 NOK
Specifications
Antigen | CHCHD6 |
---|---|
Clone | 2A11E9 |
Concentration | 1 mg/mL |
Applications | Western Blot |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16808625
|
Proteintech
66597-1-IG-20UL |
20 μL |
1611.84 NOK
20µL |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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16898615
|
Proteintech
66597-1-IG-150UL |
150 μL |
4593.76 NOK
150µL |
Estimated Shipment: 08-05-2024 Log in to see stock. |
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Description
CHCHD6 is a member of a family of proteins containing a conserved (coiled coil 1)-(helix 1)-(coiled coil 2)-(helix 2) domain and has been observed in a complex with the mitochondrial proteins mitofilin, SAM50, metaxins 1 and 2, and CHCHD3. CHCHD6 knockdown causes severe defects in mitochondrial cristae morphology as well as reductions in cell growth, ATP production and oxygen consumption. This decrease of CHCHD6 also led to a reduction in mitofilin protein levels, while a knockdown of mitofilin resulted in a reduced level of CHCHD6, suggesting coordinate regulation between these two proteins. CHCHD6 knockdown in human cancer cells enhances their sensitivity to genotoxic anticancer drugs, suggesting that CHCHD6 may be a potential therapeutic anti-tumor target.Specifications
CHCHD6 | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
CHCHD6 | |
CHCHD6 | |
IgG2a | |
Protein A | |
Antibody |
2A11E9 | |
Western Blot | |
Unconjugated | |
Mouse | |
Human | |
Q9BRQ6 | |
84303 | |
CHCHD6 Fusion Protein Ag14700 | |
Primary | |
-20°C | |
CHCHD6 |