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  8. CEP-28122 mesylate salt, MedChemExpress

CEP-28122 mesylate salt, MedChemExpress

Product Code. 16407426
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Product Code. 16407426

Brand: Medchem Express HY18030A

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Description

MedChemExpress CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1.9 nM for recombinant ALK kinase activity. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity.

CEP-28122 mesylate salt, a diaminopyrimidine derivative, is a potent, selective, and orally bioavailable ALK inhibitor, with an IC50 value of 1.9 nM for recombinant ALK kinase activity. CEP-28122 has antitumor activity in experimental models of ALK-positive human cancers. CEP-28122 mesylate salt has good pharmacodynamic and pharmacokinetic activity.

Specifications

Chemical Name or Material CEP-28122 mesylate salt
Color Off-White
Purity Grade Notes Research
Molecular Formula C29H39ClN6O6S
Quantity 100 mg
Solubility Information DMSO : ≥ 6.4 mg/mL (10.08 mM)
SMILES O=C([C@H]1[C@](C2)([H])C=C[C@]2([H])[C@H]1NC3=NC(NC4=CC=C5C(CC[C@@H](N6CCOCC6)CC5)=C4OC)=NC=C3Cl)N.O=S(C)(O)=O
Molecular Weight (g/mol) 635.17
Formula Weight 635.17
Percent Purity 99.85%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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