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Thermo Scientific™ CellSensor™ SIE-bla HEK293T Cell Line

Product Code. 10216363
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Quantity:
1 vial
Unit Size:
Each
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Product Code. 10216363

Brand: Thermo Scientific™ K1649B

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Description

The CellSensor™ SIE-bla HEK 293T cell line contains a beta-lactamase reporter gene under control of the SIE response element stably integrated into HEK 293T cells.

The cell line was created through sorting by FACS of cells responsive to stimulation of the SIE pathway with interleukin 6 (IL-6). The cell line was validated for DMSO tolerance, incubation time with stimulant, and substrate loading conditions. The CellSensor™ SIE-bla HEK 293T cell line responds to agonist treatment as expected from literature and can be adapted for high throughput screening for agonists or antagonists of the SIE pathway with compound libraries. Candidate drugs can also be tested for dose response against this cell line. Academic and non-profit customers, please inquire for special pricing.

TRUSTED_SUSTAINABILITY

Specifications

Cell State Dividing Cells
Content And Storage CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use.
Quantity 1 vial
Type Cell Line
Cell Line HEK 293T
System Type CellSensor™
Druggable Target Signaling Pathway

For Research Use Only. Not for use in diagnostic procedures.

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