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Thermo Scientific™ CellSensor™ IL1-bla ECV304 Cell Line
Description
The CellSensor™ IL-1-bla ECV304 cell line is an adherent human urinary bladder cell line used to measure the (IL-1) signaling pathway via transcriptional regulation of the beta-lactamase gene. IL-1 cytokine cell signaling is a critical pathway involved in immune and inflammatory responses. This cell line was constructed using GenomeScreen™ technology utilizing a promoterless beta-lactamase reporter gene randomly integrated into the genome of the IL-1-bla ECV304 cell line. Sequential rounds of sorting were performed to isolate cell clones containing tagged genes induced by IL-1. A dose response assay was run with this cell line using IL-1 as the agonist. Academic and non-profit customers, please inquire for special pricing.
Specifications
Specifications
| Assay Entry | Cell-based beta lactamase reporter gene |
| Cell State | Dividing Cells |
| Content And Storage | CellSensor™ Cell Lines are shipped on dry ice. Store in liquid nitrogen immediately upon receipt, or thaw for immediate use. |
| For Use With (Application) | Cytokines, Signaling Pathway |
| Product Line | CellSensor |
| Quantity | 1 Vial |
| Target Entry | Interleukin 1 pathway, IRAK |
| Type | Dividing Cells |
| System Type | CellSensor™ |
| Druggable Target | Signaling Pathway |
For Research Use Only. Not for use in diagnostic procedures.
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