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TOKU-E™ Cefotaxime ReadyMade™ Solution

Product Code. 30044051
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10 x 1 mL
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Product Code. 30044051 Supplier TOKU-E™ Supplier No. C29310x1ML

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Description

Cefotaxime ReadyMade™ Solution is provided as a filter-sterilized solution of Cefotaxime Sodium in water.

  • CAS Number: 64485-93-4
  • Molecular Formula: C16H16N5NaO7S2
  • Molecular Weight: 447.45 g/mo
  • Storage Conditions: -20°C
  • Form: Liquid
  • Source: Semi-synthetic (Acremonium sp.)
  • Spectrum: Cefotaxime Sodium has broad-spectrum activity against a wide variety of Gram-positive and Gram-negative bacteria. However, unlike many cephalosporin antibiotics, Cefotaxime Sodium is not effective against Pseudomonas aeruginosa
  • Mechanism of Action: Like β-lactams, cephalosporins interfere with PBP (penicillin binding protein) activity involved in the final phase of peptidoglycan synthesis. PBPs are enzymes which catalyze a pentaglycine crosslink between alanine and lysine residues providing additional strength to the cell wall. Without a pentaglycine crosslink, the integrity of the cell wall is severely compromised and ultimately leads to cell lysis and death. Resistance to cephalosporins is commonly due to cells containing plasmid encoded β-lactamases. Cefotaxime Sodium however, is largely resistant to β-lactamases

Specifications

Chemical Name or Material Cefotaxime
Physical Form Liquid
CAS 64485-93-4
Source Semi-synthetic (Acremonium sp.)
Packaging 2 mL plastic vial
Sterile Filtered Yes, 0.22 μm
Sterility Sterile
Color Colorless
Concentration 100 to 105 mg/mL
Quantity 10 x 1 mL
Purity Grade Notes >95% (HPLC)
Assay Percent Range 916 to 964 μg/mL
Assay Percent Notes Cefotaxime Sodium, Dried Basis
Molecular Formula C16H16N5O7S2 ∙ Na
Product Line ReadyMade™ Solutions
Shipping Condition Ice Pack
Solubility Information Soluble in Water
IUPAC Name Sodium [6r-[6α,7β(z)]]-3-(acetoxymethyl)-7-[(2-aminothiazol-4-yl) (methoxyimino)acetamido]-8- oxo -5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate
Molecular Weight (g/mol) 477.45 g/mol
Formula Weight 477.45 amu
Percent Purity >95%
Grade Antibiotic
Concentration or Composition (by Analyte or Components) Cefotaxime Sodium ≥10%, Water ≤90%
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