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  7. 17100512

CD66a (CEACAM1) Monoclonal Antibody (CC1), eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 14-0661-95

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Product Code. 17100512

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Description

Description

The MAb CC1 recognizes CD66a, also known as carcinoembryonic antigen-related cell adhesion molecule 1 (CEACAM1), biliary glycoprotein, and BPG. Expression of CD66a is found on brush borders, epithelial, and endothelial cells. In hematopoietic cells expression is found abundantly on B cells, as well as some NKs, monocytes, DCs, and granulocytes. Although low levels of mRNA have been identified in T cells in humans, resting mouse T lymphocytes are not reported to express CD66a, as confirmed by lack of staining with CC1 antibody. In humans, expression levels of CD66a have been used to identify malignancies. CD66a plays a key role as a regulator of BCR activation of B lymphocytes. An alternate allele, CEACAM1b, is expressed in SJL mice; therefore, CC1 does not stain SJL tissue. The monoclonal CC1 has been shown to block viral infection and also enhance B cell proliferation when combined with IgM crosslinking.

CD66a (CEACAM1) Monoclonal antibody specifically detects CD66a (CEACAM1) in Mouse samples. It is validated for Flow Cytometry, Functional Assay, Immunohistochemistry (Paraffin), Western Blot
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD66a (CEACAM1)
Monoclonal
0.5 mg/mL
PBS with 0.09% sodium azide; pH 7.2
P31809
Mouse
10 mg
Primary
Mouse
Antibody
IgG1 κ
Flow Cytometry, Functional Assay, Immunohistochemistry (Paraffin), Western Blot
CC1
Unconjugated
CEACAM1
antigen CD66; ATP-dependent taurocolate-carrier protein; bb-1; BGP; BGP1; BGP-1; BGPI; BGPR; Biliary glycoprotein 1; Biliary glycoprotein D; bone gamma-carboxyglutamic acid (Gla) protein; carcinoembryonic antigen 1; carcinoembryonic antigen 7; carcinoembryonic antigen related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1; carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein); Cc1; C-CAM; C-CAM 105; Ccam1; CD66a; CD66a antigen; Cea1; Cea-1; Cea7; Cea-7; CEACAM1; CEA-related cell adhesion molecule 1; CEA-related cell adhesion molecule 1 (bone gamma-carboxyglutamic acid (Gla) protein) (osteocalcin); cell-CAM 105; Ecto-ATPase; GP110; hepatitis virus (MHV-4) susceptibility; hepatitis virus receptor; Hv2; Hv-2; mCEA1; Mhv-1; MHVR; MHV-R; MHVR1; mmCGM1; mmCGM1a; mmCGM2; Murine hepatitis virus receptor; osteocalcin; pp120; pp120/ecto-ATPase
Affinity chromatography
RUO
26365
4° C
Liquid
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