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  6. CD54 (ICAM-1) Monoclonal Antibody (HA58), NovaFluor™ Yellow 610, eBioscience™, Invitrogen™

CD54 (ICAM-1) Monoclonal Antibody (HA58), NovaFluor™ Yellow 610, eBioscience™, Invitrogen™

Product Code. p-7226377
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Quantity:
100 Tests
25 Tests
Unit Size:
Pack of 100
Pack of 25
Product Code. Quantity unitSize
17669146 25 Tests Pack of 25
17619156 100 Tests Pack of 100
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Product Code. 17669146

Brand: Invitrogen H035T02Y03

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Description

Mouse Monoclonal Antibody

ICAM-1 (CD54) is an 85-110 kDa single-chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. ICAM-1 has 7 potential N-linked glycosylation sites and shares considerable amino acid sequence homology with ICAM-3 (CD50) and ICAM-2 (CD102). ICAM-1 binds to integrins of type CD11a/CD18 (leukocyte adhesion molecule, LFA-1), or CD11b/CD18 (Mac-1) and is exploited by Rhinovirus as a receptor. ICAM-1 is expressed by activated endothelial cells and detected on epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils, with lower levels that increase upon inflammation. ICAM-1 is also detected in some carcinoma and melanoma cells. Soluble ICAM-1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD54 (ICAM-1)
Applications Flow Cytometry
Classification Monoclonal
Clone HA58
Concentration 0.4 μg/Test
Conjugate NovaFluor Yellow 610
Formulation PBS with 0.09% sodium azide; pH 7.2
Gene ICAM1
Gene Accession No. P05362
Gene Alias BB2; CD54; cell surface glycoprotein P3.58; Human rhinovirus receptor; ICAM; Icam1; ICAM-1; ICAM-1; CD54 homolog; Intercellular adhesion molecule 1; intercellular adhesion molecule 1 (CD54), human rhinovirus receptor; intercellular adhesion molecule-1; intercellular adhesion molecule-1 precursor; Ly 47; Ly-47; major group rhinovirus receptor; MALA2; MALA-2; MyD10; P3.58; sCD54; soluble CD54; Surface antigen of activated B cells
Gene Symbols ICAM1
Host Species Mouse
Purification Method Affinity chromatography
Quantity 25 Tests
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 3383
Target Species Human
Content And Storage 4° C, store in dark, DO NOT FREEZE!
Product Type Antibody
Form Liquid
Isotype IgG1 κ
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