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CD5 Monoclonal Antibody (UCHT2), Super Bright™ 436, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
1470.00 NOK - 3555.00 NOK
Specifications
Antigen | CD5 |
---|---|
Clone | UCHT2 |
Concentration | 5 μL/Test |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
---|---|---|---|---|---|---|---|---|---|
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15805483
|
Affymetrix eBioscience
62-0059-42 |
100 Tests |
3555.00 NOK
Pack of 100 |
Estimated Shipment: 16-05-2024 Log in to see stock. |
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15895473
|
Affymetrix eBioscience
62-0059-41 |
25 Tests |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The UCHT2 monoclonal antibody reacts with human CD5, a 67 kDa protein expressed by a majority of thymocytes and mature T cells and a subset of B cells. Signaling through the CD5 molecule activates T cells and binding of CD5 to its ligand on B cells, CD72, and plays an important role in T-B interaction and proliferation. The monoclonal antibody UCHT2 recognizes primate CD5. Applications Reported: This UCHT2 antibody has been reported for use in flow cytometric analysis. Applications Tested: This UCHT2 antibody has been pre-diluted and tested by flow cytometric analysis of normal human peripheral blood cells. This may be used at 5 μL (0.5 μg) per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Super Bright 436 can be excited with the violet laser line (405 nm) and emits at 436 nm. We recommend using a 450/50 bandpass filter, or equivalent. Please make sure that your instrument is capable of detecting this fluorochrome. When using two or more Super Bright dye-conjugated antibodies in a staining panel, it is recommended to use Super Bright Staining Buffer (Product No. SB-4400) to minimize any non-specific polymer interactions. Please refer to the datasheet for Super Bright Staining Buffer for more information. Excitation: 405 nm; Emission: 436 nm; Laser: Violet Laser
CD5 is a 67 kDa human T-lymphocyte single-chain transmembrane glycoprotein. CD5 is present on all mature T-lymphocytes, on most of thymocytes and on many T-cell leukemias and lymphomas. CD5 also reacts with a subpopulation of activated B-cells and may act as a receptor in regulating T-cell proliferation. CD5 is found on 95% of thymocytes and 72% of peripheral blood lymphocytes. In lymph nodes, the main reactivity is observed in T cell areas. CD5 is expressed by many T cell leukemia, lymphomas, and activated T cells. Diseases associated with CD5 dysfunction include thymus cancer and Richter's Syndrome.Specifications
CD5 | |
5 μL/Test | |
Monoclonal | |
Liquid | |
RUO | |
PBS with BSA and 0.09% sodium azide; pH 7.2 | |
921 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
UCHT2 | |
Flow Cytometry | |
Super Bright 436 | |
Mouse | |
Human | |
P06127 | |
CD5 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! | |
CD5 |
For Research Use Only