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  6. CD45R (B220) Rat, anti-Mouse, Unconjugated, Clone: RA3-6B2, STEMCELL Technologies

CD45R (B220) Rat, anti-Mouse, Unconjugated, Clone: RA3-6B2, STEMCELL Technologies

Product Code. p-7218201
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Quantity:
100 μg
500 μg
Unit Size:
100µg
500µg
Product Code. Quantity unitSize
17107591 100 μg 100µg
17168501 500 μg 500µg
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Product Code. 17107591

Brand: Stemcell Technologies 1000422

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Description

Rat Monoclonal Antibody

  • The RA3-6B2 antibody reacts with an epitope on the extracellular domain of the exon A‐restricted isoform of mouse CD45
  • CD45 is a member of the protein tyrosine phosphatase family and functions in a number of immunoregulatory processes, including cell activation, growth, differentiation, and oncogenic transformation
  • The large cytoplasmic portion of CD45 contains two tyrosine phosphatase domains (one of which is enzymatically active) that are involved in modulating the function of Src kinases such as Lck and Fyn
  • Several isoforms of CD45 have been identified, the expression of which differs according to cell type and functional status
  • Alternative splicing of three exons encoding the extracellular RA, RB, and RC polypeptide sequences gives rise to up to 8 isoforms with molecular masses in the range of 200 - 220 kDa
  • This antibody clone has been verified for purity assessments of cells isolated with EasySep™ kits, including EasySep™ Mouse B Cell Isolation Kit (Catalog #19854)

Specifications

Antigen CD45R (B220)
Applications Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence
Classification Monoclonal
Clone RA3-6B2
Conjugate Unconjugated
Host Species Rat
Quantity 100 μg
Primary or Secondary Primary
Target Species Feline, Human, Mouse
Cell Type B Cells, Leukocytes, Lymphocytes
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