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CD355 (CRTAM) Monoclonal Antibody (Cr24.1), APC, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
Brand: Affymetrix eBioscience 17-3559-42
Additional Details : Weight : 0.01000kg
Description
This monoclonal antibody Cr24.1 reacts with human CD355, also known as Class-I MHC-restricted T-cell-associated molecule (CRTAM). CD355 usually exists as a homodimer, however, it forms a heterodimer with its ligand Necl-2. CD355 is transiently expressed by activated NK, NKT, gamma delta T, and CD8+ T cells. CD355 is also expressed by Purkinje neurons. Human CD355 is involved in immunosurveillance of cancer cells, gamma delta T cell survival, cell polarity, retention of lymphocytes in lymph nodes, promotion of cytotoxicity in NK cells, and IFN gamma secretion from CD8+ T cells. Cr24.1 has been reported to have antagonist activity. This Cr24.1 antibody has been pre-titrated and tested by flow cytometric analysis of stimulated normal human peripheral blood cells. This can be used at 5 µL (1 µg) per test. A test is defined as the amount (µg) of antibody that will stain a cell sample in a final volume of 100 µL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. Filtration: 0.2 μm post-manufacturing filtered.
The CRTAM gene is upregulated in CD4-positive and CD8-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains.Specifications
| CD355 (CRTAM) | |
| Monoclonal | |
| 5 μL/Test | |
| PBS with 0.2% BSA and 0.09% sodium azide | |
| O95727 | |
| CRTAM | |
| Transfected CRTAM-P815 cells | |
| 100 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG2a κ |
| Flow Cytometry | |
| Cr24.1 | |
| APC | |
| CRTAM | |
| CD355; CD355 antigen; class I MHC restricted T cell associated molecule; class I-restricted T cell-associated molecule; class-I MHC-restricted T cell associated molecule; class-I MHC-restricted T-cell-associated molecule; Crtam; cytotoxic and regulatory T cell molecule; cytotoxic and regulatory T-cell molecule | |
| Mouse | |
| Affinity chromatography | |
| RUO | |
| 56253 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
For Research Use Only.