Learn More
CD3 Mouse, anti-Human, RB780, Clone: UCHT1 (also known as UCHT-1; UCHT 1), BD Horizon™
Description
The UCHT1 monoclonal antibody specifically binds to the human CD3ε-chain, a 20-kDa subunit of the CD3/T cell antigen receptor complex. CD3ε is expressed on 70-80% of normal human peripheral blood lymphocytes and 60-85% of thymocytes. Studies from the HLDA Workshop show that this antibody is mitogenic for CD3ε-positive cells when used in conjunction with costimulatory agents such as pokeweed mitogen or anti-CD28 antibody. CD3 plays a central role in signal transduction during antigen recognition. The UCHT1 antibody stains both surface and intracellular CD3ε unlike the other CD3 clone, HIT3a, that stains only extracellular CD3ε.
Specifications
Specifications
| Antigen | CD3 |
| Applications | Flow Cytometry |
| Clone | UCHT1 (also known as UCHT-1; UCHT 1) |
| Conjugate | RB780 |
| Formulation | Aqueous buffered solution containing ≤0.09% sodium azide |
| Host Species | Mouse |
| Immunogen | Human infant thymocytes and peripheral blood lymphocytes from a Sézary Syndrome donor |
| Quantity | 100 Tests |
| Regulatory Status | RUO |
| Primary or Secondary | Secondary |
| Show More |
By clicking Submit, you acknowledge that you may be contacted by Fisher Scientific in regards to the feedback you have provided in this form. We will not share your information for any other purposes. All contact information provided shall also be maintained in accordance with our Privacy Policy.