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Description
CD3 is a multimeric protein associated with the T-cell receptor (TCR) to form a complex involved in antigen recognition and signal transduction (PMID: 15885124). CD3 is composed of CD3γ, δ, ε, and ζ chains (PMID: 1826255). It is expressed by thymocytes in a developmentally regulated manner, T cells, and some NK cells (PMID: 3289580). The TCR recognizes antigens bound to major histocompatibility complex (MHC) molecules. TCR-mediated peptide-MHC recognition is transmitted to the CD3 complex, leading to the intracellular signal transduction (PMID: 11985657).
Specifications
Specifications
| Antigen | CD3 |
| Applications | Flow Cytometry |
| Classification | Monoclonal |
| Clone | SK7 |
| Concentration | 5 μL/Test |
| Conjugate | CoraLite 488 |
| Host Species | Mouse |
| Quantity | 100 Tests |
| Primary or Secondary | Primary |
| Gene ID (Entrez) | 916 |
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