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CD140a (PDGFRA) Monoclonal Antibody (APA5), Functional Grade, eBioscience™, Invitrogen™
Description
The APA5 MAb reacts with the mouse CD140a molecule, the alpha chain of the platelet derived growth factor receptor (PDGF receptor). PDGFRa is a receptor tyrosine kinase that forms dimers on the surface upon ligand binding and phosphorylates substrates. Dimers of PDGFR consist of either homodimers of alpha/alpha, beta/beta, or heterodimers of alpha/beta and serve as a substrate for its kinase activity. CD140a is expressed by embryonic tissues and mesenchymal-derived cells of the adult mouse tissues.
Specifications
Specifications
| Antigen | CD140a (PDGFRA) |
| Applications | Flow Cytometry, Functional Assay, Immunohistochemistry (Frozen), Neutralization, Western Blot |
| Classification | Monoclonal |
| Clone | APA5 |
| Concentration | 1 mg/mL |
| Conjugate | Functional Grade |
| Formulation | PBS with no preservative; pH 7.2 |
| Gene | PDGFRA |
| Gene Accession No. | P26618 |
| Gene Alias | AI115593; Alpha platelet-derived growth factor receptor; Alpha platelet-derived growth factor receptor precursor (PDGF-R-alpha); alpha-type platelet-derived growth factor receptor; APDGFR; CD140 antigen-like family member A; CD140a; CD140a antigen; GAS9; MGC74795; OTTHUMP00000218656; PDGF A-chain; PDGF alpha chain; PDGF Receptor alpha; PDGF subunit A; PDGF-1; PDGFACE; PDGFR2; Pdgfr-2; PDGFRA; pdgfr-a; PDGFRA/BCR fusion; PDGF-R-alpha; PDGFR-alpha; platelet derived growth factor receptor alpha; platelet derived growth factor receptor, alpha polypeptide; platelet-derived growth factor alpha receptor; Platelet-derived growth factor receptor 2; platelet-derived growth factor receptor alpha; platelet-derived growth factor receptor, alpha polypeptide; rearranged-in-hypereosinophilia-platelet derived growth factor receptor alpha fusion protein; RHEPDGFRA |
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