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CD134 Rat anti-Mouse, CoraLite 488, Clone: OX-86, Proteintech

Product Code. 17214696 Shop All Proteintech Products
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Quantity:
100 Tests
Unit Size:
100 reactions
Product Code. Quantity unitSize
17214696 100 Tests 100 reactions
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Product Code. 17214696

Brand: Proteintech CL48865136100TESTS

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Description

Rat Monoclonal Antibody

CD134, also known as OX40 and TNFRSF4, is a member of the TNFR-superfamily of receptors (PMID: 2828930; 9766631). It is a type I transmembrane protein predominantly expressed on activated T cells which include CD4 and CD8 T cells, Th2, Th1, and Th17 cells, as well as regulatory T cells (Tregs) (PMID: 20307208). CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule (PMID: 26215166). CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmune diseases, cancer and infectious disease (PMID: 26215166; 19426222).

Specifications

Antigen CD134
Applications Flow Cytometry
Classification Monoclonal
Clone OX-86
Concentration 5 μL/Test
Conjugate CoraLite 488
Host Species Rat
Quantity 100 Tests
Primary or Secondary Primary
Gene ID (Entrez) 22163
Target Species Human, Mouse, Rat
Form Liquid
Isotype IgG1 κ
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