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CD134 (OX40) Monoclonal Antibody (OX-86), Functional Grade, eBioscience™, Invitrogen™
Description
The OX-86 MAb reacts with mouse CD134, also known as OX40. A member of the TNF receptor superfamily, CD134 is a 50 kDa type I membrane glycoprotein expressed by activated mouse T lymphocytes. Rat CD134 was initially identified as an activation marker only on activated CD4+ T cells. In contrast, mouse CD134 is expressed by both activated CD4+ and CD8+ T cells. The interaction of CD134 with CD252 (OX40 ligand) has been implicated in T cell-dependent humoral responses, regulation of primary T cell expansion, survival of T cells, size of the memory T cell pool, and regulation of tolerance in the CD4+ T cell compartment.
Specifications
Specifications
| Antigen | CD134 (OX40) |
| Applications | Flow Cytometry, Functional Assay |
| Classification | Monoclonal |
| Clone | OX-86 |
| Concentration | 1 mg/mL |
| Conjugate | Functional Grade |
| Formulation | PBS with no preservative; pH 7.2 |
| Gene | Tnfrsf4 |
| Gene Accession No. | P47741 |
| Gene Alias | ACT35; ACT35 antigen; ATC35 antigen; CD134; CD134 antigen; IMD16; Ly-70; lymphoid activation antigene ACT35; MRC OX40; Ox40; OX40 antigen; OX40 cell surface antigen; OX40 homologue; OX40L receptor; TAX transcriptionally-activated glycoprotein 1 receptor; tax-transcriptionally activated glycoprotein 1; tax-transcriptionally activated glycoprotein 1 receptor; TNF receptor superfamily member 4; TNFRSF4; tumor necrosis factor (ligand) superfamily member 4; tumor necrosis factor receptor superfamily member 4; tumor necrosis factor receptor superfamily, member 4; tumor necrosis factor superfamily, member 4; Txgp1; TXGP1L |
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