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  6. CD11b/Mac-1 Mouse anti-Human, PE-Cy7, Clone: ICRF44, BD

CD11b/Mac-1 Mouse anti-Human, PE-Cy7, Clone: ICRF44, BD

Product Code. 15829028
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Quantity:
100 Tests
25 Tests
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Each
Product Code. Quantity unitSize
15829028 100 Tests Each
15801239 25 Tests Each
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Product Code. 15829028

Brand: BD Biosciences 557743

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Description

Mouse Monoclonal Antibody

The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.

TRUSTED_SUSTAINABILITY

Specifications

Antigen CD11b
Applications Flow Cytometry
Classification Monoclonal
Clone ICRF44
Conjugate PE-Cyanine7
Description Mac-1α, integrin αM subunit, CR3 α chain
Formulation Aqueous buffered solution containing BSA and ≤0.09% sodium azide.
Host Species Mouse
Immunogen Human monocytes
Purification Method Affinity Purified
Quantity 100 Tests
Regulatory Status RUO
Research Discipline Immunology
Primary or Secondary Primary
Target Species Human
Content And Storage Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.
Isotype IgG1 κ
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For Research Use Only.

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