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CD106 (VCAM-1) Monoclonal Antibody (eBioMR106 (MR106)), Biotin, eBioscience™, Invitrogen™
Mouse Monoclonal Antibody
892.00 NOK - 1670.00 NOK
Specifications
Antigen | CD106 (VCAM-1) |
---|---|
Clone | eBioMR106 (MR106) |
Concentration | 0.5 mg/mL |
Applications | Flow Cytometry |
Classification | Monoclonal |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
15219679
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Affymetrix eBioscience
13-1060-82 |
100 μg |
1670.00 NOK
100µg |
Estimated Shipment: 06-06-2024 Log in to see stock. |
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15209679
|
Affymetrix eBioscience
13-1060-81 |
50 μg |
This item is currently unavailable or has been discontinued. View the product page for possible alternatives. |
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Description
Description: The eBioMR106 monoclonal antibody reacts with rat CD106 (Vascular Cell Adhesion Molecule-1, VCAM-1), a 110 kDa transmembrane glycoprotein expressed by myeloid lineage and bone marrow stromal cells. Endothelial cells constitutively express low levels of CD106 and further upregulate VCAM-1 upon cytokine stimulation. CD106 binds to integrin alpha4beta1 (VLA-4, CD49d/CD29) and Integrin alpha4beta7 (LPAM-1) and these interactions in the bone marrow and thymus are important for early lymphocyte and myeloid development. Cytokine-mediated upregulation of CD106 on endothelial cells suggests a role for this antigen in the inflammatory response. Applications Reported: This eBioMR106 (MR106) antibody has been reported for use in flow cytometric analysis. Applications Tested: This eBioMR106 (MR106) antibody has been tested by flow cytometric analysis of rat bone marrow cells. This can be used at less than or equal to 0.25 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Filtration: 0.2 μm post-manufacturing filtered.
VCAM-1 is a cell surface sialoglycoprotein expressed by cytokine activated endothelium. The protein has a number of functions including the regulation of leukocyte migration, leukocyte-endothelial cell adhesion and signal transduction and may play a role in a number of inflammatory diseases.Specifications
CD106 (VCAM-1) | |
0.5 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
P29534 | |
IgG1 κ | |
Affinity chromatography | |
Antibody |
eBioMR106 (MR106) | |
Flow Cytometry | |
Biotin | |
Mouse | |
Rat | |
25361 | |
Primary | |
4° C, store in dark, DO NOT FREEZE! |
For Research Use Only.