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CD105 (Endoglin) Monoclonal Antibody (SN6), Functional Grade, eBioscience™, Invitrogen™

Mouse Monoclonal Antibody

Brand:  Affymetrix eBioscience 16-1057-025

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Product Code. 17101112

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Description

Description

The SN6 monoclonal antibody reacts with human CD105, also known as Endoglin. CD105, an approximately 90 kDa disulfide-linked homodimer is expressed by vascular endothelial cells and some bone marrow cells and activated macrophages. It is suggested that CD105 functions in adhesion and embryonic angiogenesis. Applications Reported: This SN6 antibody has been reported to have functional activity. Applications Tested: This SN6 antibody has been tested by flow cytometric analysis of U937 cell line. This can be used at less than or equal to 1 μg per test. A test is defined as the amount (μg) of antibody that will stain a cell sample in a final volume of 100 μL. Cell number should be determined empirically but can range from 10^5 to 10^8 cells/test. It is recommended that the antibody be carefully titrated for optimal performance in the assay of interest. Storage and handling: Use in a sterile environment. Filtration: 0.2 μm post-manufacturing filtered. Purity: Greater than 90%, as determined by SDS-PAGE. Endotoxin Level: Less than 0.001 ng/ μg antibody, as determined by LAL assay. Aggregation: Less than 10%, as determined by HPLC.

CD105 (Endoglin) Monoclonal antibody specifically detects CD105 (Endoglin) in Human samples. It is validated for Functional Assay
TRUSTED_SUSTAINABILITY
Specifications

Specifications

CD105 (Endoglin)
Monoclonal
1 mg/mL
PBS with no preservative; pH 7.2
P17813
Mouse
25 mg
Primary
Human
Antibody
IgG1 κ
Functional Assay
SN6
Functional Grade
ENG
AI528660; AI662476; CD105; CD105 antigen; cell surface MJ7/18 antigen; Edg; END; Endo; Endoglin; endoglin (Osler-Rendu-Weber syndrome 1); ENG; HHT1; ORW; ORW1; S-endoglin; transmembrane glycoprotein
Affinity chromatography
RUO
2022
4° C
Liquid
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