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CBR-5884, MedChemExpress

Product Code. 16494196
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Product Code. Quantity unitSize
16494196 100 mg 100mg
16475477 5 mg 5mg
16459436 50 mg 50mg
16452738 10 mg 10mg
16432516 25 mg 25mg
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Product Code. 16494196

Brand: Medchem Express HY100012

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Description

MedChemExpress CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis.

CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis.

Specifications

Chemical Name or Material CBR-5884
Physical Form Solid
CAS 681159-27-3
Color Yellow
Quantity 100 mg
Purity Grade Notes Research
Molecular Formula C14H12N2O4S2
For Use With (Application) Cancer-programmed cell death
Solubility Information DMSO : 50 mg/mL (148.64 mM; Need ultrasonic)
SMILES O=C(C1=C(C)C(SC#N)=C(NC(C2=CC=CO2)=O)S1)OCC
Molecular Weight (g/mol) 336.39
Formula Weight 336.39
Percent Purity 98.74%
Grade Research
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Research purposes only

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