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Caveolin-1 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 6C2B2, Proteintech
Shop All Proteintech ProductsDescription
Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.
Specifications
Specifications
| Antigen | Caveolin-1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | 6C2B2 |
| Concentration | 0.74 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 |
| Gene | CAV1 |
| Gene Accession No. | P41350, P49817, Q03135, Q6RVA9 |
| Gene Symbols | CAV1 |
| Show More |
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