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Caveolin-1 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 6C2B2, Proteintech

Product Code. 16847605 Shop All Proteintech Products
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150 μL
20 μL
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150µL
20µL
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16847605 150 μL 150µL
16857605 20 μL 20µL
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Product Code. 16847605 Supplier Proteintech Supplier No. 660671IG150UL

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Mouse Monoclonal Antibody

Caveolin-1 or CAV1 is a scaffolding proteins within caveolar membranes. It interacts directly with G-protein alpha subunits and can functionally regulate their activity. Caveolin-1 is also involved in the co-stimulatory signal essential for T-cell receptor (TCR) mediated T-cell activation. It can bind with DPP4 and induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. Mutations affecting the CAV1 gene can result in congenital generalized lipodystrophy 3, pulmonary hypertension primary 3, or partial lipodystrophy/congenital cataracts, and neurodegeneration syndrome.

Specifications

Antigen Caveolin-1
Applications Immunohistochemistry (Paraffin), Western Blot
Classification Monoclonal
Clone 6C2B2
Concentration 0.74 mg/mL
Conjugate Unconjugated
Formulation PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
Gene CAV1
Gene Accession No. P41350, P49817, Q03135, Q6RVA9
Gene Symbols CAV1
Host Species Mouse
Immunogen Caveolin-1 Fusion Protein Ag8049
Purification Method Protein G
Quantity 150 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 12389, 25404, 404693, 857
Target Species Human, Mouse, Pig, Rat
Content And Storage -20°C
Product Type Antibody
Form Liquid
Isotype IgG1
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