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Calsequestrin 2 Mouse anti-Human, Mouse, Porcine, Rat, Clone: 1C10A1, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66419-1-IG-150UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888275

  • 3468.15 NOK / 150µL
Estimated Shipment: 20-12-2022
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Description

Description

Calsequestrin (CASQ) is a Ca2+-binding protein present primarily in junctional sarcoplasmic reticulum of skeletal and cardiac muscle; the cardiac form (CASQ2) is encoded by a separate gene. The primary role of CASQ2 is buffering of the sarcoplasmic reticulum Ca2+ ions, but another role for CASQ2 has emerged recently: CASQ2 regulates the open probability of ryanodine receptor 2 (RyR2). Mutations in CASQ2 cause stress-induced polymorphic ventricular tachycardia, also referred to as catecholaminergic polymorphic ventricular tachycardia 2 (CPVT2), a disease characterized by bidirectional ventricular tachycardia that may lead to cardiac arrest.
Specifications

Specifications

Calsequestrin 2
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3
O09161, O14958, O18934, P51868
Casq2
Calsequestrin 2 Fusion Protein Ag13246
150 μL
Primary
Rat, Porcine, Mouse, Human
Antibody
IgG2a
Western Blot, Immunohistochemistry (Paraffin)
1C10A1
Unconjugated
CASQ2
Calsequestrin 2, CASQ2, PDIB2
Mouse
Protein A
RUO
12373, 29209, 397436, 845
-20°C
Liquid
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SDS
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Documents

Certificates
Special Offers

Special Offers