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Calponin Mouse anti-Human, Clone: 1A11E5, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66540-1-IG-150UL

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Product Code. 16898505

  • 4593.76 NOK / 150µL

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Description

Description

This antibody raised against the specific region of human CNN1, thus it does not cross-react with CNN2 or CNN3.

Calponin, a thin filament associated protein is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin, troponin C and tropomyosin. Calponin is expressed in smooth muscle and tissues containing significant amounts of smooth muscle. Two isoforms of calponin exist whose molecular weights are 34kDa and 29kDa. Expression of the 29kDa form is primarily restricted to muscle of the urogenital tract. The expression of calponin has also been demonstrated in myoepithelial cells from benign and maligt breast lesions. It stains smooth muscle, myoepithelial cells, myofibroblasts, keratinocytes and nerve fibers. It identifies myoepithelial cells in breast lesions, and helps differentiate breast collagenous spherulosis (positive) from adenoid cystic carcinoma. Adenoid cystic carcinoma in salivary gland tumors is calponin positive.
Specifications

Specifications

Calponin
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P51911
CNN1
Calponin Fusion Protein Ag21384
150 μL
Primary
Human
Antibody
IgG2b
Immunohistochemistry (Paraffin), Western Blot
1A11E5
Unconjugated
CNN1
Basic calponin, Calponin 1, Calponin H1, smooth muscle, CNN1, Sm Calp, SMCC
Mouse
Protein A
RUO
1264
-20°C
Liquid
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