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c-Cbl Mouse anti-Human, Clone: 2F6D1, Proteintech

Mouse Monoclonal Antibody

Brand:  Proteintech 66576-1-IG-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888575

  • 1281.92 NOK / 20µL
Estimated Shipment: 13-12-2022
to see stock.

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Description

Description

Cbl proteins are a family of ubiquitin protein ligases (E3s) that negatively regulate signaling by targeting activated tyrosine kinases for degradation. Cbl- c is the most recently cloned member of the Cbl proteins and is expressed only in epithelial cells (the other Cbl proteins are ubiquitously expressed). Cbl-c, like the other mammalian Cbl proteins, can ubiquitinate the activated EGFR and target it for degradation. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling.
Specifications

Specifications

c-Cbl
Monoclonal
1 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
P22681
CBL
c-Cbl Fusion Protein Ag23033
20 μL
Primary
Human
Antibody
IgG1
Western Blot, Immunohistochemistry (Paraffin)
2F6D1
Unconjugated
CBL
C CBL, CBL, CBL2, c-Cbl, Proto oncogene c Cbl, RING finger protein 55, RNF55
Mouse
Protein G
RUO
867
-20°C
Liquid
Videos
SDS
Documents
Certificates
Special Offers

Special Offers