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Brepocitinib P-Tosylate, MedChemExpress

Product Code. p-200098393
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Product Code. 16485516 Supplier Medchem Express Supplier No. HY112708A

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Description

MedChemExpress Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.

Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively.

Specifications

Chemical Name or Material Brepocitinib P-Tosylate
CAS 2140301-96-6
Color White
Purity Grade Notes Research
Molecular Formula C25H29F2N7O4S
Quantity 100 mg
Synonym PF-06700841 P-Tosylate
Solubility Information DMSO : 62.5 mg/mL (111.29 mM; Need ultrasonic)
SMILES O=C([C@H]1C(F)(F)C1)N2C3CN(C4=NC(NC5=CN(C)N=C5)=NC=C4)CC2CC3.O=S(C6=CC=C(C)C=C6)(O)=O
Molecular Weight (g/mol) 561.6
Formula Weight 561.6
Percent Purity 99.69%
Grade Research
Physical Form Solid
For Use With (Application) COVID-19-immunoregulation
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Research purposes only

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