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BRAF Mouse anti-Human, Clone: OTI4B2, lyophilized, TrueMAB™
Mouse Monoclonal Antibody
Brand: Origene Technologies CF500438
Additional Details : Weight : 0.05000kg
Description
Reconstitute with PBS (pH 7.3) and recommend to perform another round of desalting process using Product No. 7KMWCO
B-raf belongs to the raf/mil family of serine/threonine protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion. Mutations in the gene are associated with cardiofaciocutaneous syndrome, a disease characterized by heart defects, mental retardation and a distinctive facial appearance. Mutations in this gene have also been associated with various cancers, including non-Hodgkin lymphoma, colorectal cancer, maligt melanoma, thyroid carcinoma, non-small cell lung carcinoma, and adenocarcinoma of lung. A pseudogene, which is located on chromosome X, has been identified for this gene.Specifications
BRAF | |
Monoclonal | |
Unconjugated | |
BRAF | |
B-RAF1, B-raf, BRAF1, NS7, RAFB1 | |
Mouse | |
Affinity Chromatography | |
RUO | |
673 | |
-20° C, Avoid Freeze/Thaw Cycles | |
Lyophilized |
Western Blot | |
OTI4B2 | |
PBS with 8% trehalose and no preservative; pH 7.3 | |
P15056 | |
BRAF | |
Full-length protein expressed in 293T cell transfected with human BRAF expression vector | |
100 μg | |
Primary | |
Human | |
Antibody | |
IgG2a |