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Invitrogen™ BNIP3 Recombinant Rabbit Monoclonal Antibody (JA71-10)
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Description
BNIP3 Recombinant Monoclonal Antibody for ICC/IF, IHC (P), Western Blot
NIP3 is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. NIP3 contains a BH3 domain and a transmembrane domain, which have been associated with pro-apoptotic function. The dimeric mitochondrial protein is known to induce apoptosis, even in the presence of BCL2.
Specifications
Specifications
| Antigen | BNIP3 |
| Applications | Immunohistochemistry (Paraffin), Western Blot, Immunocytochemistry |
| Classification | Recombinant Monoclonal |
| Clone | JA71-10 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | TBS with 40% glycerol, 0.05% BSA and 0.05% sodium azide; pH 7.4 |
| Gene | BNIP3 |
| Gene Accession No. | O55003, Q12983 |
| Gene Alias | BCL2 interacting protein 3; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B 19 kDa-interacting protein 3; BCL2/adenovirus E1B 19kDa interacting protein 3; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B interacting protein 1, NIP3; BCL2/adenovirus E1B interacting protein 3; Bnip3; NIP3 |
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