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ACROBiosystems Biotinylated Human TACI / TNFRSF13B Protein, Fc, Avitag™

Biotinylated Protein

Brand:  ACROBiosystems TAI-H82F6-200ug

Additional Details : Weight : 0.00010kg

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Product Code. 16448089

  • 19250.81 NOK / 200µg
Estimated Shipment: 11-01-2023
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Description

Description

Transmembrane activator and CAML interactor (TACI), also known as tumor necrosis factor receptor superfamily member 13B (TNFRSF13B). It was originally discovered because of its ability to interact with calcium-modulator and cyclophilin ligand (CAML). TACI was later found to play a crucial role in humoral immunity by interacting with two members of the TNF family: BAFF and APRIL. The present study demonstrated that, in NSCLC, a proliferation-inducing ligand (APRIL), B-cell maturation antigen (BCMA)and transmembrane activator and CAML interactor (TACI) proteins are abnormally expressed by immunohistochemistry, reverse transcription-quantitative polymerase chain reaction and western blotting. In addition, the expression of APRIL, BCMA and TACI were observed to be involved in extracellular signal-regulated kinase (ERK)1/2 activation in A549 cells.

This protein carries a human IgG1 Fc tag at the C-terminus, followed by a Avi tag (Avitag™). The protein has a calculated MW of 46.7 kDa. The protein migrates as 33-40 kDa and 47-50 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Specifications

Specifications

NP_036584.1
46.7 kDa
200 µg
Ser 2 - Thr 166
CD267,TACI,TNFRSF13B
Precision Avi
Tris with Glycine, Arginine and NaCl, pH7.5
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Biotinylated Human TACI, Fc,Avitag (TAI-H82F6) is expressed from human 293 cells (HEK293). It contains AA Ser 2 - Thr 166 (Accession # O14836-1).
-20°C
TACI
Fc Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
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