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Invitrogen™ BCL11A Polyclonal Antibody

Product Code. 15514902
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Quantity:
100 μL
Unit Size:
100µL
Product Code. Quantity unitSize
15514902 100 μL 100µL
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Product Code. 15514902

Brand: Invitrogen™ PA541589

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This item is not returnable. View return policy

Description

Rabbit Polyclonal Antibody

Peptide sequence: MSRRKQGKPQ HLSKREFSPE PLEAILTDDE PDHGPLGAPE GDHDLLTCGQ Sequence homology: Cow: 100%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%; Zebrafish: 100%.

This gene encodes a C2H2 type zinc-finger protein by its similarity to the mouse Bcl11a/Evi9 protein. The corresponding mouse gene is a common site of retroviral integration in myeloid leukemia, and may function as a leukemia disease gene, in part, through its interaction with BCL6. During hematopoietic cell differentiation, this gene is down-regulated. It is possibly involved in lymphoma pathogenesis since translocations associated with B-cell malignancies also deregulates its expression. Multiple transcript variants encoding several different isoforms have been found for this gene.
TRUSTED_SUSTAINABILITY

Specifications

Antigen BCL11A
Applications Immunohistochemistry, Western Blot
Classification Polyclonal
Concentration 0.5 mg/mL
Conjugate Unconjugated
Formulation PBS with 2% sucrose and 0.09% sodium azide
Gene BCL11A
Gene Accession No. Q9H165
Gene Alias 2810047E18Rik; B cell CLL/lymphoma 11A; B cell CLL/lymphoma 11A (zinc finger protein); BAF chromatin remodeling complex subunit BCL11A; B-cell CLL/lymphoma 11A; B-cell CLL/lymphoma 11A (zinc finger protein); B-cell CLL/lymphoma 11A (zinc finger protein) isoform 2; B-cell lymphoma/leukemia 11A; BCL11A; BCL-11A; BCL11A B-cell CLL/lymphoma 11A (zinc finger protein) isoform 1; BCL11A, BAF complex component; BCL11A-L; BCL11a-M; BCL11A-S; BCL11A-XL; C2H2-type zinc finger protein; COUP-TF interacting protein 1; COUP-TF-interacting protein 1; CTIP1; D930021L15Rik; ecotropic viral integration site 9 homolog; ecotropic viral integration site 9 protein; Ecotropic viral integration site 9 protein homolog; Evi9; EVI-9; Evi9a; Evi9b; Evi9c; FLJ10173; FLJ34997; HBFQTL5; Kiaa1809; mKIAA1809; myeloid leukemia; zinc finger protein 856; ZNF856
Gene Symbols BCL11A
Host Species Rabbit
Immunogen Synthetic peptide directed towards the N-terminal of human BCL11A (aa 1-50).
Purification Method Affinity Chromatography
Quantity 100 μL
Regulatory Status RUO
Primary or Secondary Primary
Gene ID (Entrez) 53335
Target Species Human
Content And Storage -20°C, Avoid Freeze/Thaw Cycles
Product Type Antibody
Form Liquid
Isotype IgG
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