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Description
Bcl-6 proto-oncogene product (a Kruppel-type zinc-finger protein) is mainly expressed in normal germinal center B cells and related lymphomas. Bcl-6 is involved in chromosome rearrangements at 3q27 in non-Hodgkin's lymphomas and Bcl-6 rearrangements have been detected in 33%-45% of diffuse large B cell lymphomas. Bcl-6 has been detected immunohistochemically in follicular lymphomas, diffuse large B cell lymphomas, Burkitt's lymphomas and in nodular, lymphocyte predominant Hodgkin's disease.
Host Species: Mouse
Clone: BL6.02, same as PG-B6p
Isotype: IgG1/κ
Species Reactivity: Human, Cow, Rabbit, Rat, Sheep and Pig. Others not tested.
Epitope: aa 3-484
Immunogen: Recombinant protein corresponding to amino acids 3-484 of the human Bcl-6 protein
Positive Control: Tonsil
Cellular Localization: Nuclear
Recommended for:
- Immunohistochemistry (Formalin/paraffin)
Note:
USA: RUO; Int'l: RUO
Specifications
Specifications
| Antigen | Bcl-6 Ab-2 |
| Applications | Immunohistochemistry (Paraffin) |
| Classification | Monoclonal |
| Clone | BL6.02; same as PG-B6p |
| Conjugate | Unconjugated |
| Host Species | Mouse |
| Immunogen | Recombinant protein corresponding to amino acids 3-484 of the human Bcl-6 protein |
| Purification Method | Tonsil |
| Quantity | 1 mL |
| Regulatory Status | RUO |
| Show More |
Product Title
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