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Proteintech BCCIP Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 16043-1-AP-20UL
Additional Details : Weight : 0.00010kg
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DescriptionThis gene product was isolated on the basis of its interaction with BRCA2 and p21 proteins. It is an evolutionarily conserved nuclear protein with multiple interacting domains. The N-terminal half shares moderate homology with regions of calmodulin and M-calpain, suggesting that it may also bind calcium. Functional studies indicate that this protein may be an important cofactor for BRCA2 in tumor suppression, and a modulator of CDK2 kinase activity via p21. This protein has also been implicated in the regulation of BRCA2 and RAD51 nuclear focus formation, double-strand break-induced homologous recombination, and cell cycle progression. Multiple transcript variants encoding different isoforms have been described for this gene.
|BCCIP, Protein TOK 1, TOK 1, TOK1|
|Antigen Affinity Chromatography|
|361666, 56647, 66165|
|Western Blot, Immunoprecipitation, Immunocytochemistry, Immunofluorescence|
|PBS with 50% glycerol and 0.02% sodium azide; pH 7.3|
|BCCIP Fusion Protein Ag8934|
|Rat, Human, Mouse|