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BAY 11-7082, MedChemExpress
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Quantity:
5 mg
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100 mg
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5mg
Description
BAY 11-7082 selectively and irreversibly inhibits the TNF-α-induced phosphorylation of IκB-α, and decreases NF-κB and expression of adhesion molecules. BAY 11-7082 inhibits ubiquitin-specific protease USP7 and USP21 (IC50=0.19, 0.96 μM, respectively). BAY 11-7082 inhibits gasdermin D (GSDMD) pore formation in liposomes and inflammasome-mediated pyroptosis and IL-1β secretion in human and mouse cells.
Specifications
Specifications
| Chemical Name or Material | BAY 11-7082 |
| CAS | 19542-67-7 |
| Color | White |
| Purity Grade Notes | Research |
| Molecular Formula | C10H9NO2S |
| Quantity | 100 mg |
| Synonym | BAY 11-7821 |
| Solubility Information | DMSO : ≥ 100 mg/mL (482.51 mM) |
| SMILES | N#C/C=C/S(=O)(C1=CC=C(C)C=C1)=O |
| Molecular Weight (g/mol) | 207.25 |
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Research purposes only
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