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BAG3 Rabbit anti-Human, Mouse, Rat, Polyclonal, Proteintech
Rabbit Polyclonal Antibody
Brand: Proteintech 10599-1-AP-150UL
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Description
BAG3 are among BAG proteins that compete with Hip for binding to the Hsc70/Hsp70 ATPase domain and promote substrate release. All the BAG proteins have an approximately 45-amino acid BAG domain near the C terminus but differ markedly in their N-terminal regions. The protein encoded by this gene contains a WW domain in the N-terminal region and a BAG domain in the C-terminal region. The BAG domains of BAG1, BAG2, and BAG3 interact specifically with the Hsc70 ATPase domain in vitro and in mammalian cells. All 3 proteins bind with high affinity to the ATPase domain of Hsc70 and inhibit its chaperone activity in a Hip-repressible manner.Specifications
| BAG3 | |
| Polyclonal | |
| Unconjugated | |
| BAG3 | |
| BAG 3, BAG3, BIS, CAIR 1, Docking protein CAIR 1 | |
| Rabbit | |
| Antigen Affinity Chromatography | |
| RUO | |
| 293524, 29810, 9531 | |
| -20°C | |
| Liquid |
| Immunocytochemistry, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Western Blot | |
| 0.48 mg/mL | |
| PBS with 50% glycerol and 0.1% sodium azide; pH 7.3 | |
| O95817, Q9JLV1 | |
| BAG3 | |
| BAG3 Fusion Protein Ag0956 | |
| 150 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |