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AZ304, MedChemExpress
MedChemExpress AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79 nM, 38 nM and 68 nM, respectively. AZ304 also has significant effect on other kinases, such as p38 (IC50, 6 nM), CSF1R (IC50, 35 nM). Anti-tumor activity.
3271.37 NOK - 5231.03 NOK
Specifications
Chemical Name or Material | AZ304 |
---|---|
CAS | 942507-42-8 |
Color | White |
Purity Grade Notes | Research |
Molecular Formula | C27H25N5O2 |
Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
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Product Code | Brand | Quantity | Price | Quantity & Availability | |||||
16435656
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Medchem Express
HY-117273 |
100 mg |
5231.03 NOK
100mg |
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16431127
![]() |
Medchem Express
HY-117273 |
50 mg |
3271.37 NOK
50mg |
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Description
AZ304 is an ATP-competitive dual BRAF kinase inhibitor, potently inhibits wild type BRAF, V600E mutant BRAF and wild type CRAF, with IC50s of 79 nM, 38 nM and 68 nM, respectively. AZ304 also has significant effect on other kinases, such as p38 (IC50, 6 nM), CSF1R (IC50, 35 nM). Anti-tumor activity.Specifications
AZ304 | |
White | |
C27H25N5O2 | |
O=C(NC1=CC=C(C)C(NC2=C3C=CC(OC)=CC3=NC=N2)=C1)C4=CC=CC(C(C)(C#N)C)=C4 | |
451.52 | |
Research | |
Cancer-Kinase/protease |
942507-42-8 | |
Research | |
DMSO : 125 mg/mL (276.84 mM; Need ultrasonic) | |
451.52 | |
99.96% | |
Solid |
Safety and Handling
missing translation for 'shelfLife' : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Recommended Storage : Powder -20°C 3 years, 4°C 2 years∣In solvent -80°C 6 months, -20°C 1 month
Research purposes only
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