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Invitrogen™ Atrophin 1 Monoclonal Antibody (C1), Invitrogen™
Description
Dentatorubral pallidoluysian atrophy (DRPLA) is a rare neurodegenerative disorder characterized by cerebellar ataxia, myoclonic epilepsy, choreoathetosis, and dementia. The disorder is related to the expansion from 7-35 copies to 49-93 copies of a trinucleotide repeat (CAG/CAA) within this gene. The encoded protein includes a serine repeat and a region of alternating acidic and basic amino acids, as well as the variable glutamine repeat. Alternative splicing results in two transcripts variants that encode the same protein.
Specifications
Specifications
| Antigen | Atrophin 1 |
| Applications | Immunohistochemistry (Paraffin), Western Blot |
| Classification | Monoclonal |
| Clone | C1 |
| Concentration | 1 mg/mL |
| Conjugate | Unconjugated |
| Formulation | PBS with 50% glycerol and 0.05% ProClin 300; pH 7.4 |
| Gene | ATN1 |
| Gene Accession No. | P54259 |
| Gene Alias | ATN1; Atr1; atrophin 1; Atrophin1; atrophin-1; B37; D12S755E; dentatorubral pallidoluysian atrophy; dentatorubral-pallidoluysian atrophy protein; Dentatorubral-pallidoluysian atrophy protein homolog; Drpla; HRS; NOD |
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