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  8. AST 487, MedChemExpress

AST 487, MedChemExpress

Product Code. p-200097838
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Quantity:
5 mg
10 mg
50 mg
Unit Size:
10mg
50mg
5mg
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Product Code. 16488867

Brand: Medchem Express HY15002

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Description

MedChemExpress AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.

AST 487 is a RET kinase inhibitor with IC50 of 880 nM, inhibits RET autophosphorylation and activation of downstream effectors, also inhibits Flt-3 with IC50 of 520 nM.

Specifications

Chemical Name or Material AST 487
CAS 630124-46-8
Color White
Purity Grade Notes Research
Molecular Formula C26H30F3N7O2
Quantity 5 mg
Synonym NVP-AST 487
Solubility Information DMSO : ≥ 100 mg/mL (188.84 mM)
SMILES O=C(NC1=CC=C(OC2=NC=NC(NC)=C2)C=C1)NC3=CC=C(CN4CCN(CC)CC4)C(C(F)(F)F)=C3
Molecular Weight (g/mol) 529.56
Formula Weight 529.56
Percent Purity 99.2%
Grade Research
Physical Form Solid
For Use With (Application) Cancer-Kinase/protease
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Research purposes only

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