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ARHGEF1 Rabbit anti-Human, Mouse, Polyclonal, Proteintech

Rabbit Polyclonal Antibody

Brand:  Proteintech 11363-1-AP-20UL

Additional Details : Weight : 0.00010kg

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Product Code. 16888383

  • 1281.92 NOK / 20µL
Estimated Shipment: 19-12-2022
to see stock.

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Description

Description

The Ras superfamily of GTPases, which can be subdivided into the Ras, Rho/Rac, Sar, Rab, ARF and Ran subfamilies, controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. The Ras superfamily of GTPases function as regulated switches that toggle between a biologically active GTP-bound and an inactive GDP-bound form. This activation is catalyzed by guanine nucleotide exchange factors (GEFs). The Dbl-related proteins are a large family of structurally related molecules that have a common ability to catalyze GEF activity for specific members of the Ras family. Dbl-related proteins include FGD1, Lsc, RhoGEF p115, Lfc, Lbc and Brx. Lsc, Lbc and Lfc share sequence homology and show exchange activity toward Rho family GTPases. RhoGEF p115 catalyzes GEF activity for Rho but not Rac, Cdc42 or Ras GTPases.
Specifications

Specifications

ARHGEF1
Polyclonal
Unconjugated
ARHGEF1
ARHGEF1, GEF1, LBCL2, LSC, P115 RHOGEF, p115RhoGEF, SUB1.5
Rabbit
Antigen Affinity Chromatography
RUO
16801, 9138
-20°C
Liquid
Western Blot, Immunofluorescence, Immunohistochemistry (Paraffin), Immunoprecipitation, Immunocytochemistry
0.39 mg/mL
PBS with 50% glycerol and 0.1% sodium azide; pH 7.3
Q61210, Q92888
ARHGEF1
ARHGEF1 Fusion Protein Ag1905
20 μL
Primary
Mouse, Human
Antibody
IgG
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