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BD Biosciences™ Anti-Human IFN-γ FITC/CD69 PE/CD4 PerCP-Cy™5.5/CD3 APC (RUO/GMP)

Product Code. 15835828
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50 Tests
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Product Code. Quantity unitSize
15835828 50 Tests Each
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Product Code. 15835828

Brand: BD Biosciences™ 337184

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Description

Monoclonal antibodies for detecting human antigens.

  • Clone SK7 (also known as Leu-4) 25723.11 L78 SK3 (also known as Leu3a) (Ruo (GMP)).
  • Anti-Hu–IFN-γ, clone 25723.11, is derived from the hybridization of mouse P3X-63- Ag8.653 myeloma cells with lymph node cells from BALB/c mice immunized with recombinant human IFN-γ.
  • CD69, clone L78, is derived from hybridization of mouse Sp2/0-Ag14 myeloma cells with lymph node cells from BALB/c mice immunized with a CD8+ alloantigen-directed cytotoxic T-lymphocyte (CTL) cell line.
  • CD4, clone SK3, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immununized with human peripheral blood T lymphocytes.
  • CD3, clone SK7, is derived from hybridization of mouse NS-1 myeloma cells with spleen cells from BALB/c mice immunized with human thymocytes.
  • Anti-Human Interferon- γ (Anti-Hu–IFN-γ) recognizes a 20- to 25-kilodalton (kd) glycoprotein.
  • CD69 recognizes a very early human activation antigen. The CD69 antigen is a surface homodimer formed by the association of 28- and 32-kd chains that are held together by disulfide bridges.
  • The CD4 antigen, Mr 55 kd, is present on T-helper/inducer lymphocytes and monocytes.
  • CD3 reacts with the epsilon chain of the CD3 antigen/T-cell antigen receptor (TCR) complex. This complex is composed of at least six proteins that range in molecular weight from 20 to 30 kd.
  • The antigen recognized by CD3 antibodies is noncovalently associated with either α/β or γ/δ TCR (70 to 90 kd).
  • Contents:
  • Specificity: CD3, Clone: SK7 (also known as Leu4), Format: APC, Isotype: IgG1K, Entrez Gen ID: 916
  • Specificity: IFN-γ, Clone: 25723.11, Format: FITC,Isotype: IgG2bK, Entrez Gen ID: 3458
  • Specificity: CD69, Clone: L78, Format: PE, Isotype: IgG1K, Entrez Gen ID: 969
  • Specificity: CD4, Clone: SK3 (also known as Leu-3a), Format: PerCP-CY™5.5, Isotype: IgG1K, Entrez Gen ID: 920
  • Research applications include the following:
    • Studies of T-cell responses to antigens such as cytomegalovirus (CMV), human immunodeficiency virus (HIV), herpes viruses, and tumor antigens.
TRUSTED_SUSTAINABILITY

Specifications

Antigen CD3, IFN-γ, CD69, CD4
Applications Flow Cytometry
Clone SK7, 25723.11, L78, SK3
Host Species Mouse
Quantity 50 Tests
Regulatory Status RUO
Includes Storage buffer: Phosphate buffered saline with BSA, beta-lactoglobulin, and 0.1% sodium azide.
Target Species Human
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